Diabetes in Pregnancy

Pregnancy is diabetogenic why?
Pregnancy is diabetogenic because during pregnancy increased insulin antagonist factor such as:-
1, Increased Oestrogen & Progesterone production
2, Placental insulinase production
3, Increase cortisol level
4, Human placental lactogen production

These subtances are insulin antagonist which leads to increase insulin resistance during pregnancy. This leads to increase insulin requirment during pregnancy.

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